APOE4 Gene Test
A simple at-home cheek swab that reveals your APOE genotype (ε2, ε3, ε4 status) with results in 2-3 weeks. Powered by a CLIA-certified genomics partner, this DNA test analyzes over 800,000 genetic variants to offer meaningful genetic insights from your unique genetic makeup. You can start with the Basic APOE (1 report), or unlock the premium Cognition+ (13 reports) for a comprehensive view of the interconnected genetic pathways that influence cognition, inflammation response, metabolic resilience, detoxification capacity, and long-term neurological performance.
- Register your kit using the easy instructions
- Complete the cheek swab and return your sample vials using the included pre-paid mailer
- Get your results in about 2 to 3 weeks delivered securely to your inbox
- If at any time, you'd like to receive additional reports, you can upgrade for more genetic insights through the portal
To learn how your genetic information is protected, please review our Genetic Testing Privacy Statement.
Product details, kit components, reporting options, and packaging are subject to change by the manufacturer and may differ from the information shown on this site. Always verify instructions and warnings on the actual product label before use. This content is for reference only and does not constitute medical advice or a diagnosis. The genetic reports are for reference only and do not constitute medical advice, a diagnosis, or a clinical genetic consultation. We recommend consulting a licensed genetic counselor or healthcare professional to interpret your results within the context of your personal and family medical history. Genetic reports have not been evaluated by the FDA and are not intended to diagnose or cure any health condition.
Why Use Fenix Gene Tests?
1 Basic APOE Report
A focused genetic report centered exclusively on your APOE genotype and allele status.
This assessment includes:
- Identification of whether you carry 0, 1, or 2 copies of APOE4
- How your genotype relates to lipid metabolism and inflammatory response
- An overview of how APOE influences the brain
- Personalized lifestyle strategies based on your genotype
Designed for individuals who only want a targeted look at their APOE status and its biological significance.
13 Cognition Reports
A comprehensive genetic panel that includes 59 genetic insights.
These assessments include:
- Everything in the Basic Report
- Risk patterns for Mild Cognitive Impairment (MCI)
- Genetics influencing hippocampal size (memory center)
- Omega-3 needs and omega-6 balance
- Insulin resistance and metabolic function
- Genes affecting vitamin B12, folate, and MTHFR activity
- Choline requirements for brain support
- Sleep duration and nighttime awakenings
- Inflammatory and metabolic resilience pathways
- Longevity and telomere length markers
Designed for those seeking a broader, systems-based view of the genetics influencing brain performance and resilience.
Why APOE4 Matters
APOE (Apolipoprotein E) is a gene that provides instructions for making a protein involved in cholesterol transport and normal brain function. Variations in this gene may influence how the APOE protein works in the body. There are three common variants of APOE: E2, E3, and E4. You inherit one variant from each parent, resulting in one of six possible combinations: E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, & E4/E4
Scientific research has identified associations between certain APOE variants and differences in cognitive health risk and Alzheimer’s. For example, E4 is associated with higher risk, while E2 may offer some protective effect. However, APOE status alone does not determine health outcomes. This test is intended for informational and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
APOE testing provides information about your specific APOE genotype, including whether you carry the E4 variant that research has associated with differences in cognitive aging risk.
Although APOE status does not diagnose or determine outcomes, it can offer useful insight into how your body may respond to factors such as inflammation, cholesterol metabolism, and long-term brain aging. For some individuals, especially those with a family history of Alzheimer’s or dementia, this information can help guide earlier and more intentional health decisions.
People often choose APOE testing to:
- Understand whether they carry zero, one, or two copies of E4
- Personalize nutrition and lifestyle strategies based on genetic insight
- Prioritize brain-supportive habits such as omega-3 intake, metabolic health, exercise, and sleep
- Have more informed discussions with healthcare providers
Research suggests that lifestyle factors play an important role in long-term cognitive health. Knowing your APOE genotype can help you make practical, informed choices aligned with your individual biology.
This test is intended for informational and educational purposes and does not diagnose, treat, cure, or prevent any disease.
Your kit includes everything needed for simple at-home DNA collection and secure processing:
Inside the box:
- 2 sterile cheek swabs
- 2 collection vials
- Biohazard specimen bag
- Prepaid return mailer
- Step-by-step collection instructions
Included with your purchase:
- Secure registration and laboratory processing by a CLIA-certified genomics partner
- Personalized APOE report(s)
- Clear interpretations with easy-to-follow recommendations
- Confidential delivery of your results
The process is designed to be convenient, secure, and easy to complete at home.
The collection process is designed to be simple, quick, and non-invasive.
Your kit includes a cheek swab that collects DNA from the inside of your mouth — no needles, no blood draw, and no lab visit required. You gently swab the inside of your cheek for a few seconds, following the step-by-step instructions included in the kit. The process is painless and typically takes just a few minutes from start to finish.
There’s no special preparation needed beyond avoiding food or drinks 60 minutes before swabbing, as directed in the instructions. Once complete, you place the swab into the provided container and mail it back using the prepaid packaging.
It’s a straightforward, non-invasive way to access advanced genetic insights — all from the comfort and privacy of your home.
Your genetic information is protected using strict privacy and security standards.
Your DNA is used only to run your test and generate your personal results. It is not sold, shared for advertising, or used for unrelated research purposes.
Testing and analysis are conducted by a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption, and additional safeguards are in place to reduce risk.
To further protect your privacy:
- Your personal identifying information is stored separately from your genetic data (data separation protocol).
- Genetic data is maintained in an anonymized genome database, meaning it is not stored in a way that directly identifies you.
- Results are shared only with you — and with your healthcare provider only if you request it.
Protecting your privacy and maintaining data security are core components of the testing process.
Take this test if you...
- Want insight into your genetics related to brain health
- Have a family history of dementia or Alzheimer’s
- Want to be proactive about long-term cognitive wellness
- Want personalized nutrition and lifestyle guidance
- Want actionable insights—not just raw genetic data
- Prefer non-invasive testing without bloodwork
How To Take the Test
Upgrade Anytime
You can begin with a focused single-gene report , such as the basic APOE4, and unlock additional genetic reports through the portal whenever you choose. Your initial cheek swab captures your full genomic dataset, so you do not need to submit another sample to access expanded reports.
Simply pay the difference between your current test and the additional report or panel you would like to add. You are never charged more for starting with a focused option and expanding later.
Expanded reports provide deeper genetic insights across multiple biological systems, including brain health and cognition, sleep patterns, nutrition and micronutrient needs, hormone pathways, inflammation response, detoxification capacity, cardiometabolic health, longevity, and performance-related genetics.
Frequently Asked Questions
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Results are delivered in approximately 2–3 weeks after your sample is received by the lab.
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Yes, your genetic information is used only to run your test and generate your personal results—it is not sold, shared for advertising, or used for unrelated research. Testing is processed by a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption and data separation (your personal details are stored separately from your genetic data) to reduce risk even further. Genetic information is stored in an anonymized genome database, meaning it is not kept in a way that directly identifies you. Results are shared only with you (and your provider if you request it).
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Yes. Upon withdrawal of consent, data is securely deleted from active systems. Some backups may take additional time to be purged, but they are removed according to our scheduled deletion processes.
It is standard practice in the genetic labs using Illumina machines in the USA to keep unprocessed data in a fully anonymized form. These labs do not have access to the system that identifies the person with their sample—all they have is an ID number. The lab retains a copy of raw genetic data for clients to support interpretation and report generation. -
Yes. You can unlock additional genetic reports anytime using the same test kit. No need to swab twice, just unlock the additional reports after your results are in.
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No. The reports are designed to be easy to understand, but they are also practitioner-friendly if you choose to share the results with your doctor.
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Register your kit immediately after receiving it.
Your barcode number is the only way to identify your sample. If it is not recorded and registered correctly, you will not receive your results.To Register:
- Scan the QR code included in your kit or visit: app.fenixhealthscience.com
- Complete the registration form and enter:
- Your name
- Email address
- A password (you create this)
- Your 8-character barcode starting with “MR” - Carefully write down your barcode.
- Take a photo of your registration code and keep it for your records.
Registration creates your account so you can access your results once they are available.
- Scan the QR code included in your kit or visit: app.fenixhealthscience.com
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Step 1: Scan the QR code in your kit or visit app.fenixhealthscience.com to begin registration.
Step 2: Complete the registration form by entering your:
- Name
- Email address
- Password (you create this)
- 8-character barcode starting with “MR”
Important:
- Carefully write down your barcode.
- Take a picture of your registration code and keep it for your records.
This creates your account so you can view results once available.
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For at least 60 minutes before collection, do NOT:
- Eat
- Drink (except plain water)
- Brush your teeth
- Use mouthwash
- Use oils
- Use oral analgesics
- Use adhesives
- Use tobacco or nicotine
Drinking plain water is okay. - Eat
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Your results are generated through a CLIA- and CAP-certified laboratory, two of the highest standards for clinical lab quality and accuracy. The testing and reporting process is backed by a multidisciplinary team spanning genetics, molecular biology, bioinformatics, clinical research, and medical data science. Just as importantly, the interpretation system is continuously refined using current, peer-reviewed scientific research and validated sources. The end goal is to provide results that are both technically reliable and translated into clear, evidence-based insights you can actually use in clinical and wellness decisions.
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Log in at https://app.fenixhealthscience.com/login where you registered your test kit to view your results.
You will log in with the email and password you used in registering your kit. Then make sure Results is selection on the left menu and click though the tabs at the top marked All, Reports, and Bundles to find your report.
If you need any assistance, please contact us at info@fenixhealthscience.com and send us your kit registration code in the email.
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