APOE4 Gene Test
Basic APOE (1 Report)
Simple line drawing of a house icon
At-Home Testing
Person swabbing cheek for DNA
Easy Collection
Icon of a shield with a check mark inside, symbolizing security or approval.
Secure Results
Icon of a test tube with a DNA double helix inside
CLIA- & CAP-certified lab
Icon of a document with HIPAA label and checkboxes
HIPAA & GDPR standards
What's Included with our

1 Basic APOE Report

A focused genetic report centered exclusively on your APOE genotype and allele status.


This assessment includes:

  • Identification of whether you carry 0, 1, or 2 copies of APOE4
  • How your genotype relates to lipid metabolism and inflammatory response
  • An overview of how APOE influences the brain
  • Personalized lifestyle strategies based on your genotype

Designed for individuals who only want a targeted look at their APOE status and its biological significance.

What's Included with our

13 Cognition Reports

A comprehensive genetic panel that includes 59 genetic insights.

These assessments include:

  • Everything in the Basic Report
  • Risk patterns for Mild Cognitive Impairment (MCI)
  • Genetics influencing hippocampal size (memory center)
  • Omega-3 needs and omega-6 balance
  • Insulin resistance and metabolic function
  • Genes affecting vitamin B12, folate, and MTHFR activity
  • Choline requirements for brain support
  • Sleep duration and nighttime awakenings
  • Inflammatory and metabolic resilience pathways
  • Longevity and telomere length markers

Designed for those seeking a broader, systems-based view of the genetics influencing brain performance and resilience.

Man swabbing cheek while taking a genetic test
Green DNA double helix icon on a white background

Why APOE4 Matters

The APOE gene helps your body move and use fats, including in the brain. Since the brain relies heavily on healthy fat metabolism, APOE can play an important role in long-term cognitive health.

The APOE4 variant has been linked to a higher risk of cognitive decline and Alzheimer’s, as well as differences in how the brain uses DHA (omega-3s).

APOE4 is not a diagnosis, but knowing your status can help you make more informed nutrition and lifestyle choices to better support brain health over time.

APOE Test Details

APOE (Apolipoprotein E) is a gene that provides instructions for making a protein involved in cholesterol transport and normal brain function. Variations in this gene may influence how the APOE protein works in the body. There are three common variants of APOE: E2, E3, and E4. You inherit one variant from each parent, resulting in one of six possible combinations: E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, & E4/E4

Scientific research has identified associations between certain APOE variants and differences in cognitive health risk and Alzheimer’s. For example, E4 is associated with higher risk, while E2 may offer some protective effect. However, APOE status alone does not determine health outcomes. This test is intended for informational and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

Learn More

APOE testing provides information about your specific APOE genotype, including whether you carry the E4 variant that research has associated with differences in cognitive aging risk.

Although APOE status does not diagnose or determine outcomes, it can offer useful insight into how your body may respond to factors such as inflammation, cholesterol metabolism, and long-term brain aging. For some individuals, especially those with a family history of Alzheimer’s or dementia, this information can help guide earlier and more intentional health decisions.

People often choose APOE testing to:

  • Understand whether they carry zero, one, or two copies of E4
  • Personalize nutrition and lifestyle strategies based on genetic insight
  • Prioritize brain-supportive habits such as omega-3 intake, metabolic health, exercise, and sleep
  • Have more informed discussions with healthcare providers

Research suggests that lifestyle factors play an important role in long-term cognitive health. Knowing your APOE genotype can help you make practical, informed choices aligned with your individual biology.

This test is intended for informational and educational purposes and does not diagnose, treat, cure, or prevent any disease.

Learn more

Your kit includes everything needed for simple at-home DNA collection and secure processing:

Inside the box:

  • 2 sterile cheek swabs
  • 2 collection vials
  • Biohazard specimen bag
  • Prepaid return mailer
  • Step-by-step collection instructions

Included with your purchase:

  • Secure registration and laboratory processing by a CLIA-certified genomics partner
  • Personalized APOE report(s)
  • Clear interpretations with easy-to-follow recommendations
  • Confidential delivery of your results

The process is designed to be convenient, secure, and easy to complete at home.

The collection process is designed to be simple, quick, and non-invasive.

Your kit includes a cheek swab that collects DNA from the inside of your mouth — no needles, no blood draw, and no lab visit required. You gently swab the inside of your cheek for a few seconds, following the step-by-step instructions included in the kit. The process is painless and typically takes just a few minutes from start to finish.

There’s no special preparation needed beyond avoiding food or drinks 60 minutes before swabbing, as directed in the instructions. Once complete, you place the swab into the provided container and mail it back using the prepaid packaging.

It’s a straightforward, non-invasive way to access advanced genetic insights — all from the comfort and privacy of your home.

Your genetic information is protected using strict privacy and security standards.

Your DNA is used only to run your test and generate your personal results. It is not sold, shared for advertising, or used for unrelated research purposes.

Testing and analysis are conducted by a clinical laboratory partner that operates under HIPAA and GDPR privacy standards. Your data is protected using multi-level encryption, and additional safeguards are in place to reduce risk.

To further protect your privacy:

  • Your personal identifying information is stored separately from your genetic data (data separation protocol).
  • Genetic data is maintained in an anonymized genome database, meaning it is not stored in a way that directly identifies you.
  • Results are shared only with you — and with your healthcare provider only if you request it.

Protecting your privacy and maintaining data security are core components of the testing process.

Take this test if you...

  • Want insight into your genetics related to brain health
  • Have a family history of dementia or Alzheimer’s
  • Want to be proactive about long-term cognitive wellness
  • Want personalized nutrition and lifestyle guidance
  • Want actionable insights—not just raw genetic data
  • Prefer non-invasive testing without bloodwork

How To Take the Test

Easy, At-home Testing

No lab visit, no appointments required—just a simple test you can take entirely at home, on your own schedule and in your own space.

Private and Secure Data

Your data is protected with advanced safeguards so your genetic information remains fully confidential and in your control.

Understandable Results

Your results are simply explained and don’t require medical interpretation—just straightforward insights you can use right away.

Personal Nutrition Insight

Use your genetic insights to personalize your nutrition and make lifestyle choices tailored specifically to your body’s needs.

DNA_Helix_Pink_and_Green.jpg
Access Additional Genetic Insights

Upgrade Anytime

You can begin with a focused single-gene report , such as the basic APOE4, and unlock additional genetic reports through the portal whenever you choose. Your initial cheek swab captures your full genomic dataset, so you do not need to submit another sample to access expanded reports.

Simply pay the difference between your current test and the additional report or panel you would like to add. You are never charged more for starting with a focused option and expanding later.

Expanded reports provide deeper genetic insights across multiple biological systems, including brain health and cognition, sleep patterns, nutrition and micronutrient needs, hormone pathways, inflammation response, detoxification capacity, cardiometabolic health, longevity, and performance-related genetics.

Frequently Asked Questions